Krabbe Disease
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KRABB DISEASE
Krabbe disease is a rare disorder of the central nervous system. It is one of a group of genetic disorders, which are called leukodystrophies, which affect the growth of the myelin sheath. The myelin sheath is a fatty covering acting as an insulator on the nerve fibers of the brain. Symptoms vary in severity among patients and include unexplained fevers, irritability, seizures, blindness, spasticity and paralysis. The disorder generally occurs from 3-6 months of age bur teens and adult patients are known.
Globoid Cell Leukodystophy (GLD) has two distinctive forms, infantile and adult. Infantile accounts for 85% to 90% of all occurrences. It is usually diagnosable between 6 months and 2 years. Symptoms start before 6 months, though they appear normal in first few months of life. Infantile form has 3 stages...